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Psychiatry Res. 2015 Sep 30;229(1-2):613-6. doi: 10.1016/j.psychres.2015.04.039. Epub 2015 May 19.

Mood disorders are associated with a more severe hypovitaminosis D than schizophrenia.

Author information

1
Department of Psychiatry, Sainte-Marguerite University Hospital, La Conception University Hospital, Assistance Publique - Hôpitaux de Marseille, France; Aix Marseille Université, CNRS, CRN2M UMR 7286, Marseille, France; Fondation FondaMental, Fondation de coopération scientifique en santé mentale, Créteil, France.
2
Department of Public Health, EA 3279 Research Unit, La Timone University Hospital, Assistance Publique - Hôpitaux de Marseille, Marseille, France.
3
Aix Marseille Université, CNRS, CRN2M UMR 7286, Marseille, France; Fondation FondaMental, Fondation de coopération scientifique en santé mentale, Créteil, France.
4
Aix Marseille Université, CNRS, NICN, UMR7259, 13344, Marseille, France.
5
Fondation FondaMental, Fondation de coopération scientifique en santé mentale, Créteil, France; University Paris Est-Créteil, GHU Mondor, DHU Pe-Psy, INSERM U955, Eq 15, Créteil, France.
6
Fondation FondaMental, Fondation de coopération scientifique en santé mentale, Créteil, France; University Paris Est-Créteil, GHU Mondor, DHU Pe-Psy, INSERM U955, Eq 15, Créteil, France. Electronic address: guillaume.fond@gmail.com.

Abstract

Patients with psychiatric disorders display high levels of hypovitaminosis D (<50nmol/L). It remains unclear whether it is associated with specific diagnoses. To further explore vitamin D status in psychiatric inpatients, 82 individuals with mood disorders or schizophrenia/schizoaffective disorders were included. Hypovitaminosis D was significantly lower in patients with mood disorders than patients with schizophrenia (standardized β coefficient=0.385, p=0.007). Further studies are warranted to determine specific causes of hypovitaminosis D and the interest of supplementation.

KEYWORDS:

Bipolar disorders; Dysthymia; Major depression; Schizophrenia; Vitamin D

PMID:
26027439
DOI:
10.1016/j.psychres.2015.04.039
[Indexed for MEDLINE]

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