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Rev Med Inst Mex Seguro Soc. 2015;53 Suppl 1:S30-5.

[Cutaneous manifestations of leukemia].

[Article in Spanish; Abstract available in Spanish from the publisher]

Author information

1
Departamento de Dermatología, Hospital de Especialidades, Centro Médico Nacional La Raza, Instituto Mexicano del Seguro Social, Distrito Federal. dra.npd@hotmail.com.

Abstract

in English, Spanish

INTRODUCTION:

To describe the type and frequency of cutaneous manifestations of leukemia.

METHODS:

Observational, descriptive study. We included patients over 16 years of age, with confirmed diagnosis of leukemia from the Hematology and Dermatology Departments of the outpatient clinic and from in-patients. Patients with bone marrow transplantation were excluded. A complete history and physical examination of the skin and appendages was performed, with biopsy and cultures if required. The cutaneous manifestations were classified as infection or drug-related, leukemic infiltration, associated dermatosis to leukemia and non-specific lesions. Descriptive statistics was employed.

RESULTS:

We included 142 patients (62 females, 80 males) with the following diagnoses: acute myeloid leukemia (n=36), acute lymphoblastic leukemia (n=52), chronic myeloid leukemia (n=21), chronic lymphocitic leukemia (n=30) and hairy cells leukemia (n=3). 42% of patients (n=60) presented some dermatoses. There were 36 non-specific dermatoses, 21 drug-related, 20 infectious, 3 infiltrative and none associated.

CONCLUSIONS:

Cutaneous manifestations directly related to leukemia are frequent, being the non-specific ones, the most commonly observed. However, a thorough dermatologic examination is important in these patients as part of an overall evaluation.

KEYWORDS:

Dermatology; Leukemia; Stem cells

PMID:
26020660
[Indexed for MEDLINE]

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