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J Psychosom Res. 2015 Sep;79(3):207-13. doi: 10.1016/j.jpsychores.2015.05.006. Epub 2015 May 18.

Somatic concerns, depressive traits, atherosclerosis and the incidence of cardiovascular disease in ageing Finnish men.

Author information

1
Department of Psychiatry, Institute of Clinical Medicine, University of Eastern Finland, P.O. Box 1627, FI-70211 Kuopio, Finland; Department of Psychiatry, Kuopio University Hospital, P.O. Box 100, FI-70211 Kuopio, Finland. Electronic address: tommi.tolmunen@kuh.fi.
2
Department of Psychiatry, Institute of Clinical Medicine, University of Eastern Finland, P.O. Box 1627, FI-70211 Kuopio, Finland; Department of Psychiatry, Kuopio University Hospital, P.O. Box 100, FI-70211 Kuopio, Finland.
3
Department of Psychiatry, Institute of Clinical Medicine, University of Eastern Finland, P.O. Box 1627, FI-70211 Kuopio, Finland; Department of Medicine, Lapland Central Hospital, P.O. Box 8041, FI-96101 Rovaniemi, Finland.
4
Department of Psychiatry, Institute of Clinical Medicine, University of Eastern Finland, P.O. Box 1627, FI-70211 Kuopio, Finland.
5
Institute of Behavioural Sciences (Psychology), University of Helsinki, P.O. Box 9, FI-00014 Helsinki, Finland.

Abstract

OBJECTIVE:

To examine the impact of somatic concerns and depressive traits on carotid artery intima-media thickness (IMT) and on the incidence of cardiovascular disease (CVD).

METHODS:

In the cross-sectional study of 2682 Finnish men aged 42 to 61years, a subsample of 1333 men had their carotid artery IMT recorded. In the prospective part of the study participants (n=1453) were followed up for an average of 20years. Data on incident CVD (n=766) were obtained from the National Population Register. For both subsamples, the Minnesota Multiphasic Personality Inventory (MMPI) was used to measure depressive traits and somatic concerns. In addition, composite scales of general ill-being, sleep and pain problems, psychological well-being, energy level, and cheerfulness were formed.

RESULTS:

In the final corrected models there were no significant associations between somatic concerns or depressive traits and IMT. Both somatic concerns and depressive traits predicted a higher CVD incidence after adjustments for age and risk factors. The association between depressive traits and CVD incidence was highest among the subgroup of men with the highest levels of hsCRP, but this result did not reach statistical significance. Of the composite scales, general ill-being predicted a higher CVD incidence in the fully adjusted model, even when all the composite scales were entered into the model simultaneously.

CONCLUSION:

Somatic concerns and depressive traits predict a higher CVD incidence. In particular, general ill-being contributes to this association. The association between depressive traits and CVD may be moderated by low-grade inflammation.

KEYWORDS:

Cardiovascular; Carotid artery; Inflammation; MMPI; Morbidity; Personality

[Indexed for MEDLINE]

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