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Int J Dev Biol. 2015;59(1-3):149-58. doi: 10.1387/ijdb.150037fs.

Regulated cell death in diagnostic histopathology.

Author information

1
Department of Pathology, University of Sarajevo Clinical Center, Sarajevo, Bosnia and Herzegovina.

Abstract

Regulated cell death (RCD) is a controlled cellular process, essential for normal development, tissue integrity and homeostasis, and its dysregulation has been implicated in the pathogenesis of various conditions including developmental and immunological disorders, neurodegenerative diseases, and cancer. In this review, we briefly discuss the historical perspective and conceptual development of RCD, we overview recent classifications and some of the key players in RCD; finally we focus on current applications of RCD in diagnostic histopathology.

PMID:
26009238
DOI:
10.1387/ijdb.150037fs
[Indexed for MEDLINE]
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