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Arch Soc Esp Oftalmol. 2015 Nov;90(11):507-16. doi: 10.1016/j.oftal.2015.03.013. Epub 2015 May 23.

Morphological characteristics of the optic nerve evaluated by confocal laser tomography (HRT3) and laser polarimetry (GDx-VCC) in a normal population from the city of Barcelona.

[Article in English, Spanish]

Author information

1
Departament d'Oftalmologia, Hospital de l'Esperança-Parc de Salut Mar, Institut Mar d'Investigacions Mèdiques , Barcelona, España; Universtitat Autònoma de Barcelona, Barcelona, España. Electronic address: mail@monicafallon.com.
2
Departament d'Oftalmologia, Hospital de l'Esperança-Parc de Salut Mar, Institut Mar d'Investigacions Mèdiques , Barcelona, España; Universtitat Autònoma de Barcelona, Barcelona, España.
3
Departament d'Investigació, Institut Català de Retina (ICR), Barcelona, España.
4
Unitat d'Infermeria, Centre d'Assistència Primària (CAP) Larrard, Barcelona, España.
5
Departament d'Oftalmologia, Hospital de l'Esperança-Parc de Salut Mar, Institut Mar d'Investigacions Mèdiques , Barcelona, España; Universtitat Autònoma de Barcelona, Barcelona, España; Departament d'Investigació, Institut Català de Retina (ICR), Barcelona, España; Universitat Internacional de Catalunya (UIC), Barcelona, España.

Abstract

OBJECTIVE:

To evaluate morphological parameters of optic disc and retinal nerve fiber layer (RNFL) examined with confocal laser tomography (HRT3) and laser polarimetry (GDx-VCC) in a normal population, and analyze correlations of these parameters with demographic variables.

PATIENTS AND METHODS:

Cross-sectional study in the context of a glaucoma screening campaign in the primary care center of Barcelona. The individuals selected were non-hypertensive Mediterranean Caucasians with risk for glaucoma development (individuals≥60 years old or≥40 years old with family history of glaucoma or intraocular pressure or myopia>3diopter). All subjects underwent a complete ophthalmic examination, confocal laser tomography (HRT3) and scanning laser polarimetry (GDX-VCC), subjects with results within normal limits only being included. Structural parameters were analyzed along with age, refraction, and pachymetry based on the Spearman rank correlation test.

RESULTS:

A total of 224 subjects included, with a mean age of 63.4±11.1 years. Disc areas, excavation and ring area were 2.14±0.52mm(2), 0.44±0.34mm (2) and 1.69±0.38mm(2), respectively. The mean RNFL (GDX) was 55.9±6.9μm. Age was correlated with lower ring volume, highest rate of cup shape measure, largest mean and maximum cup depth, lower nerve fiber index (NFI) and RNFL (all p-values below .05).

CONCLUSION:

The mean values and distribution of several parameters of the papilla and the RNFL in normal Mediterranean Caucasians population are presented. A loss of thickness of the RNFL, ring thinning, and enlarged cup was observed with increased age.

KEYWORDS:

Capa de fibras nerviosas de la retina; Glaucoma; Nervio óptico; Optic nerve head; Polarimetría láser de barrido; Retinal nerve fiber layer; Scanning laser ophthalmoscopy; Scanning laser polarimetry; Tomografía láser confocal

PMID:
26008925
DOI:
10.1016/j.oftal.2015.03.013
[Indexed for MEDLINE]

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