Format

Send to

Choose Destination
Int Ophthalmol. 2016 Feb;36(1):111-20. doi: 10.1007/s10792-015-0085-3. Epub 2015 May 26.

Progression of gyrate atrophy measured with ultra-wide-field imaging.

Author information

1
Department of Ophthalmology, Denver Health Medical Center, 777 Bannock St., Denver, CO, 80204, USA. salcedovilla@gmail.com.
2
Rocky Mountains Lions Eye Institute, University of Colorado School of Medicine, 1675 Aurora Ct., Aurora, CO, 80045, USA. salcedovilla@gmail.com.
3
Department of Ophthalmology, Denver Health Medical Center, 777 Bannock St., Denver, CO, 80204, USA.
4
Rocky Mountains Lions Eye Institute, University of Colorado School of Medicine, 1675 Aurora Ct., Aurora, CO, 80045, USA.
5
Asociación Para Evitar la Ceguera en México, Vicente García Torres # 46, 04030, Mexico, DF, Mexico.

Abstract

The study aims to determine the progression of gyrate atrophy by measuring the area growth of chorioretinal atrophic lesions using ultra-wide-field images (UWFI). A retrospective, observational, and comparative study was conducted and UWFI (200°) were obtained from two patients with gyrate atrophy at baseline and follow-up. Measurements of atrophy were obtained for three types of lesions: Solitary atrophic lesions (SAL), De novo solitary lesions (DNSL), and peripapillary atrophy (PPA). Comparison of baseline and follow-up was done using t tests. Two patients with gyrate atrophy were included. Patient 1 presented 16 SAL, 5 DNSL, and PPA measured for both eyes (BE). Overall area growth (OAG) for SAL (expressed in decimals) presented a mean of 3.41, σ 3.07. DNSL area for BE presented a mean of 1586.08 P (2), σ 1069.55. OAG for PPA presented a mean of 1.21, σ 0.17. Patient 2 presented 5 SAL, no DNSL, and PPA was measured for BE. OAG for SAL presented a mean of 1.58, σ 1.05 (range 1.02-3.47). OAG for PPA presented a mean of 1.05, σ 0.001. Gyrate atrophy progression can be determined by measuring the changes in area using UWFI.

KEYWORDS:

Choroid; Gyrate atrophy; Retina; Retina pigment epithelium; Retinal distrophies

PMID:
26003990
DOI:
10.1007/s10792-015-0085-3
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Springer
Loading ...
Support Center