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Psychiatr Clin North Am. 2015 Jun;38(2):265-79. doi: 10.1016/j.psc.2015.01.003. Epub 2015 Mar 7.

Neuropsychological assessment and differential diagnosis in young-onset dementias.

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Neurology Department, St. Adalbert Hospital, Copernicus PL Sp. z o.o., Al. Jana Pawła II 50, Gdansk 80-462, Poland; Neurological and Psychiatric Nursing Department, Medical University of Gdansk, Al. Jana Pawła II 50, Gdansk 80-462, Poland.
Neurodegenerative Department, Neurology Clinic, MSW Hospital, Wołoska 137, Warsaw 02-507, Poland.
Clinical Psychology and Neuropsychology Unit, Institute of Psychology, University of Gdansk, Bażyńskiego 4, Gdansk 80-952, Poland. Electronic address:


Although Alzheimer's disease is the most common cause of dementia in the elderly, there are several conditions (ie, frontotemporal dementia or Huntington's disease) associated with a relatively earlier onset. This article provides arguments in favor of a comprehensive neuropsychological assessment in the differential diagnosis of young-onset dementia, as episodic memory impairment is not observed early in the course of most types of young-onset dementia that predominantly affect the domains of behavior, executive, language, and/or motor function.


Alzheimer’s disease; Frontotemporal dementia; Posterior cortical atrophy; Primary progressive aphasia; Progressive supranuclear palsy

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