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Korean J Radiol. 2015 May-Jun;16(3):449-64. doi: 10.3348/kjr.2015.16.3.449. Epub 2015 May 13.

MRI features of hepatocellular carcinoma related to biologic behavior.

Author information

1
Department of Radiology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul 135-720, Korea.
2
Department of Radiology, Severance Hospital, Yonsei University College of Medicine, Seoul 120-752, Korea.

Abstract

Imaging studies including magnetic resonance imaging (MRI) play a crucial role in the diagnosis and staging of hepatocellular carcinoma (HCC). Several recent studies reveal a large number of MRI features related to the prognosis of HCC. In this review, we discuss various MRI features of HCC and their implications for the diagnosis and prognosis as imaging biomarkers. As a whole, the favorable MRI findings of HCC are small size, encapsulation, intralesional fat, high apparent diffusion coefficient (ADC) value, and smooth margins or hyperintensity on the hepatobiliary phase of gadoxetic acid-enhanced MRI. Unfavorable findings include large size, multifocality, low ADC value, non-smooth margins or hypointensity on hepatobiliary phase images. MRI findings are potential imaging biomarkers in patients with HCC.

KEYWORDS:

Hepatocellular carcinoma; Magnetic resonance imaging; Prognosis

PMID:
25995679
PMCID:
PMC4435980
DOI:
10.3348/kjr.2015.16.3.449
[Indexed for MEDLINE]
Free PMC Article

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