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Acta Radiol. 2016 Apr;57(4):413-21. doi: 10.1177/0284185115585036. Epub 2015 May 20.

MRI and comparison mammography: a worthy diagnostic alliance for breast microcalcifications?

Author information

1
Department of Diagnostic and Interventional Radiology, University Hospital Center Split, Croatia dijanaperica@yahoo.com.
2
Department of Internal Medicine, University Hospital Center Split, Croatia.
3
Department of Diagnostic and Interventional Radiology, University Hospital Center Split, Croatia.
4
Private Dermatovenerology Clinic, Split, Croatia.

Abstract

BACKGROUND:

There is a lack of data concerning diagnostic performance of magnetic resonance imaging (MRI) in patients with new or increasing microcalcifications.

PURPOSE:

To evaluate suspicious microcalcifications by using comparison mammography, MRI, and a combination of both methods.

MATERIAL AND METHODS:

Our study group consisted of 55 patients with mammographically detected BI-RADS (Breast Imaging Reporting and Data System) 3-5 microcalcifications for whom comparison mammograms were available. All patients underwent breast MRI before SVAB (stereotactic vacuum-assisted biopsy). Diagnostic performances of comparison mammography and MRI were evaluated, as well as the combination of the respective imaging findings.

RESULTS:

Of the 55 microcalcification cases, 35 showed progression and 20 were stable between interval screenings. The negative predictive value (NPV) of comparison mammography was 100%, whereas the NPV of MRI was 92%. However, the specificity of combination of findings was 97%, significantly higher than the 42% specificity of comparison mammography (P < 0.001). Additionally, the positive predictive value of combination of findings was 93% versus 44% of comparison mammography (P = 0.001).

CONCLUSION:

A biopsy is recommended when MRI positive lesion corresponding the area of new or increasing mammographic microcalcifications is detected. Patients with stable microcalcifications can continue follow-up mammography, regardless of MRI result.

KEYWORDS:

Magnetic resonance imaging (MRI); comparison; descriptors; mammography; microcalcifications; stability

PMID:
25995311
DOI:
10.1177/0284185115585036
[Indexed for MEDLINE]

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