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Nature. 2015 May 21;521(7552):E1-4. doi: 10.1038/nature14444.

Wild-type microglia do not reverse pathology in mouse models of Rett syndrome.

Author information

1
Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
2
Department of Pediatrics and Adolescent Medicine, Division of Pediatric Neurology, University Medical Center Göttingen, Robert-Koch-Strasse 40, 37075 Göttingen, Germany.
3
1] Jan and Dan Duncan Neurological Research Institute (Texas Children's Hospital), Baylor College of Medicine, Houston, Texas 77030, USA [2] Program in Developmental Biology, Baylor College of Medicine, Houston, Texas 77030, USA.
4
Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA.
5
1] Graduate Program of Neuroscience, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA [2] Department of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, Iowa 52242, USA.
6
Graduate Program of Neuroscience, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
7
Department of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, Iowa 52242, USA.
8
Department of Biochemistry, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
9
Jan and Dan Duncan Neurological Research Institute (Texas Children's Hospital), Baylor College of Medicine, Houston, Texas 77030, USA.
10
Program in Developmental Biology, Baylor College of Medicine, Houston, Texas 77030, USA.
11
Department of Pathology, University of Washington School of Medicine, Seattle, Washington 98195, USA.
12
Department of Cell &Developmental Biology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.
13
Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA.
14
Department of Neuroscience, Baylor College of Medicine, Houston, Texas 77030, USA.
15
Institute for Cellular and Molecular Immunology; University of Göttingen Medical School, Humboldtallee 34, 37073 Göttingen, Germany.
16
1] Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA [2] Department of Pathology, University of Washington School of Medicine, Seattle, Washington 98195, USA.
17
1] Program in Developmental Biology, Baylor College of Medicine, Houston, Texas 77030, USA [2] Department of Pediatrics, Baylor College of Medicine, Houston, Texas 77030, USA [3] Center for Cell and Gene Therapy, Baylor College of Medicine, Houston, Texas 77030, USA [4] Stem Cell and Regenerative Medicine Center, Baylor College of Medicine, Houston, Texas 77030, USA [5] Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA [6] Program in Translational Biology and Molecular Medicine, Baylor College of Medicine, Houston, Texas 77030, USA.
18
Department of Pathology and Laboratory Medicine, Emory University School of Medicine, Atlanta, Georgia 30322, USA.
19
1] Jan and Dan Duncan Neurological Research Institute (Texas Children's Hospital), Baylor College of Medicine, Houston, Texas 77030, USA [2] Program in Developmental Biology, Baylor College of Medicine, Houston, Texas 77030, USA [3] Department of Neuroscience, Baylor College of Medicine, Houston, Texas 77030, USA [4] Department of Pediatrics, Baylor College of Medicine, Houston, Texas 77030, USA [5] Stem Cell and Regenerative Medicine Center, Baylor College of Medicine, Houston, Texas 77030, USA [6] Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, Texas 77030, USA.
20
1] Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA [2] Department of Medicine, University of Washington School of Medicine, Seattle, Washington 98105, USA.
21
1] Department of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, Iowa 52242, USA [2] Department of Neurology, University of Iowa Carver College of Medicine, Iowa City, Iowa 52242, USA [3] Veterans Affairs, University of Iowa Carver College of Medicine, Iowa City, Iowa 52242, USA [4] Weill Cornell Autism Research Program, Weill Cornell Medical College, New York, New York 10065, USA.
PMID:
25993969
PMCID:
PMC4684952
DOI:
10.1038/nature14444
[Indexed for MEDLINE]
Free PMC Article

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