Format

Send to

Choose Destination
See comment in PubMed Commons below
Development. 1989 Apr;105(4):733-7.

An assessment of the developmental potential of embryonic stem cells in the midgestation mouse embryo.

Author information

1
ICRF Developmental Biology Unit, Department of Zoology, Oxford, UK.

Abstract

Embryonic stem cells (ES) cells were injected into host blastocysts either in groups of 10-15 cells or as single cells in order to test their developmental potential in the developing embryo. The analysis of midgestation chimaeras, by electrophoretic separation of glucose phosphate isomerase (GPI) isozymes, showed that ES cells were capable of colonizing trophectoderm and primitive endoderm derivatives at a low frequency, as well as producing a high rate of chimaerism in tissues of the fetus and extraembryonic mesoderm.

PMID:
2598811
[Indexed for MEDLINE]
Free full text
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for HighWire
    Loading ...
    Support Center