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Biosci Biotechnol Biochem. 2015;79(11):1893-7. doi: 10.1080/09168451.2015.1042833. Epub 2015 May 18.

Administration of a maple syrup extract to mitigate their hepatic inflammation induced by a high-fat diet: a transcriptome analysis.

Author information

1
a Project on Health and Anti-aging , Kanagawa Academy of Science and Technology , Kawasaki , Japan.
2
b Graduate School of Agricultural and Life Science , The University of Tokyo , Tokyo , Japan.
3
c General Research Institute , Tokyo University of Agriculture , Tokyo , Japan.

Abstract

Effects of the administration of maple syrup extract (MSX) on hepatic gene expression were investigated in mice fed a high-fat diet. Gene annotation enrichment analysis based on gene ontology revealed some changes in the expression of genes related to lipid metabolism and the immune response in MSX-fed mice. Detailed analysis of these data indicated that MSX ingestion mitigates hepatic inflammation.

KEYWORDS:

immune response; inflammation; lipid metabolism; liver; maple syrup

PMID:
25982262
DOI:
10.1080/09168451.2015.1042833
[Indexed for MEDLINE]

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