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Pain Manag. 2015;5(3):185-96. doi: 10.2217/pmt.15.8.

Best multimodal analgesic protocol for total knee arthroplasty.

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Department of Anesthesiology, Perioperative & Pain Medicine; 300 Pasteur Drive #H3580, Stanford, CA 94305 USA.


Total knee arthroplasty is one of the most commonly performed operations in the USA. As with any elective joint surgery, the primary goal includes functional restoration that is not limited by pain. The use of peripheral nerve blocks for patients undergoing knee arthroplasty has resulted in decreased pain scores, improved early ambulation and decreased time to achieve hospital discharge criteria. Concern has been raised over the potential risks of femoral nerve block, and there has been growing support for the adductor canal block. It is the author's opinion that when not contraindicated, intraoperative neuraxial anesthesia combined with a continuous adductor canal block and a multimodal medication regimen for postoperative pain control is the best analgesic protocol for knee arthroplasty.


adductor canal block; femoral nerve block; local infiltration analgesia; multimodal analgesia; perineural infusion; regional anesthesia; total knee arthroplasty

[Indexed for MEDLINE]

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