Format

Send to

Choose Destination
Biochem Biophys Res Commun. 1989 Dec 15;165(2):675-9.

NADH- and NADPH-linked aquacobalamin reductases occur in both mitochondrial and microsomal membranes of rat liver.

Author information

1
Laboratory of Nutrition and Food Science, College of Hagoromo-gakuen, Osaka, Japan.

Abstract

To elucidate the mechanism for the synthesis of the coenzyme forms of cobalamin in mammals, rat liver aquacobalamin reductase was partially characterized. Rat liver contained both NADH- and NADPH-linked aquacobalamin reductases. The NADH-linked enzyme was distributed in the mitochondria (approx. 40%) and microsomes (60%), identical to the distribution of the NADPH-linked enzyme. The two mitochondrial NADH- and NADPH-linked enzymes were located inside of the outer membrane.

PMID:
2597154
DOI:
10.1016/s0006-291x(89)80018-x
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center