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J Pharmacol Pharmacother. 2015 Apr-Jun;6(2):110-3. doi: 10.4103/0976-500X.155493.

Adrenal suppression following herbal remedy for rheumatoid arthritis.

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Department of Pharmacology, PSG College of Pharmacy, Coimbatore, Tamil Nadu, India.
Department of Pharmaceutical Chemistry, Vignan Institute of Pharmaceutical Sciences, Andhra Pradesh, India.
Department of Pharmacology, Zydus Cadila healthcare, Ahmedabad, Gujarat, India.
Department of Rheumatology, PSG Hospitals, Coimbatore, Tamil Nadu, India.
Department of Pharmacy Practice, PSG College of Pharmacy, Coimbatore, Tamil Nadu, India.


A patient suffering from rheumatoid arthritis who had extreme adrenal suppression as a result of chronic use of herbal medicines presented with complications of adrenal suppression such as muscle weakness. He also had psychiatric disturbances such as confusion and suicidal tendency. Steroids in the herbal medication were found and hence there exists a need for investigation into their safety and efficacy.


Adrenal suppression; complementary alternative medicine; rheumatoid arthritis

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