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Clin Immunol. 2015 Aug;159(2):134-42. doi: 10.1016/j.clim.2015.05.001. Epub 2015 May 9.

Gut microbes, immunity, and spondyloarthritis.

Author information

1
University of Alabama at Birmingham, CPP N 210 M, 1600 7th Avenue South, Birmingham, AL 35233-1711, USA. Electronic address: mstoll@peds.uab.edu.

Abstract

The last decade has witnessed an explosion of studies evaluating the impact of the human microbiota on a variety of disease states. The microbiota can impact diseases in multiple ways, including through abnormalities in the diversity and contents of the microbiota, as well as by acting as targets of immunologic dysregulation. Herein, evidence that the microbiota in spondyloarthritis is both altered and abnormally targeted by the immune system will be presented.

KEYWORDS:

Inflammatory bowel disease; Microbiome; Microbiota; Spondyloarthritis

PMID:
25967460
DOI:
10.1016/j.clim.2015.05.001
[Indexed for MEDLINE]

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