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Public Health Nutr. 2016 Feb;19(2):218-29. doi: 10.1017/S136898001500124X. Epub 2015 May 11.

Major dietary patterns and carotid intima-media thickness in Bangladesh.

Author information

1
1Departments of Population Health and Environmental Medicine,New York University School of Medicine,650 First Avenue,New York,NY 10016,USA.
2
3Department of Environmental Health Sciences,Mailman School of Public Health,Columbia University,New York,NY,USA.
3
4U-Chicago Research Bangladesh,Ltd,Dhaka,Bangladesh.
4
5Department of Neurology,Miller School of Medicine,University of Miami,Miami,FL,USA.
5
6Department of Epidemiology,Mailman School of Public Health,Columbia University,New York,NY,USA.
6
9Departments of Health Studies,Medicine and Human Genetics and Comprehensive Cancer Center,The University of Chicago,5841 South Maryland Avenue,Suite N102,Chicago,IL 60637,USA.

Abstract

OBJECTIVE:

Carotid intima-media thickness (IMT) is a validated surrogate marker of preclinical atherosclerosis and is predictive of cardiovascular morbidity and mortality. Research on the association between IMT and diet, however, is lacking, especially in low-income countries or low-BMI populations.

DESIGN:

Cross-sectional analysis. Dietary intakes were measured using a validated, thirty-nine-item FFQ at baseline cohort recruitment. IMT measurements were obtained from 2010-2011.

SETTING:

Rural Bangladesh.

SUBJECTS:

Participants (n 1149) randomly selected from the Health Effects of Arsenic Longitudinal Study, an ongoing, population-based, prospective cohort study established in 2000. Average age at IMT measurement was 45·5 years.

RESULTS:

Principal component analysis of reported food items yielded a 'balanced' diet, an 'animal protein' diet and a 'gourd and root vegetable' diet. We observed a positive association between the gourd/root vegetable diet and IMT, as each 1 sd increase in pattern adherence was related to a difference of 7·74 (95 % CI 2·86, 12·62) μm in IMT (P<0·01), controlling for age, sex, total energy intake, smoking status, BMI, systolic blood pressure and diabetes mellitus diagnoses. The balanced pattern was associated with lower IMT (-4·95 (95 % CI -9·78, -0·11) μm for each 1sd increase of adherence; P=0·045).

CONCLUSIONS:

A gourd/root vegetable diet in this Bangladeshi population positively correlated with carotid IMT, while a balanced diet was associated with decreased IMT.

KEYWORDS:

Atherosclerosis; Bangladesh; Carotid intima-media thickness; Diet; Dietary patterns

PMID:
25958860
PMCID:
PMC5142295
DOI:
10.1017/S136898001500124X
[Indexed for MEDLINE]
Free PMC Article

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