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Anaerobe. 2015 Aug;34:80-3. doi: 10.1016/j.anaerobe.2015.05.001. Epub 2015 May 2.

Molecular characterization and antimicrobial susceptibilities of Clostridium difficile clinical isolates from Victoria, Australia.

Author information

1
Department of Microbiology, Monash University, Clayton, VIC, Australia.
2
School of Pathology and Laboratory Medicine, The University of Western Australia, Nedlands, WA, Australia.
3
Monash Infectious Diseases, Monash Health, Clayton, VIC, Australia.
4
Department of Microbiology, Austin Health, Heidelberg, VIC, Australia; Department of Microbiology and Immunology, University of Melbourne, VIC, Australia.
5
Monash Infectious Diseases, Monash Health, Clayton, VIC, Australia; Department of Microbiology, Monash Health, Clayton, VIC, Australia.
6
School of Pathology and Laboratory Medicine, The University of Western Australia, Nedlands, WA, Australia; PathWest Laboratory Medicine, Nedlands, WA, Australia.
7
Department of Microbiology, Monash University, Clayton, VIC, Australia. Electronic address: dena.lyras@monash.edu.

Abstract

Some Australian strain types of Clostridium difficile appear unique, highlighting the global diversity of this bacterium. We examined recent and historic local isolates, finding predominantly toxinotype 0 strains, but also toxinotypes V and VIII. All isolates tested were susceptible to vancomycin and metronidazole, while moxifloxacin resistance was only detected in recent strains.

KEYWORDS:

Clostridium difficile; Clostridium difficile Australia; Clostridium difficile antibiotic resistance; Clostridium difficile epidemiology; Clostridium difficile toxinotypes

PMID:
25944720
DOI:
10.1016/j.anaerobe.2015.05.001
[Indexed for MEDLINE]

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