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Lancet. 2015 May 2;385(9979):1778-1788. doi: 10.1016/S0140-6736(15)60647-X.

Early chronic obstructive pulmonary disease: definition, assessment, and prevention.

Author information

1
Department of Internal Medicine, University of Nebraska Medical Center, Nebraska Medical Center, Omaha, NE, USA. Electronic address: srennard@unmc.edu.
2
Johns Hopkins University School of Medicine, Baltimore, MD, USA.

Abstract

Chronic obstructive pulmonary disease (COPD) is the third leading cause of death worldwide. COPD, however, is a heterogeneous collection of diseases with differing causes, pathogenic mechanisms, and physiological effects. Therefore a comprehensive approach to COPD prevention will need to address the complexity of COPD. Advances in the understanding of the natural history of COPD and the development of strategies to assess COPD in its early stages make prevention a reasonable, if ambitious, goal.

PMID:
25943942
PMCID:
PMC4819246
DOI:
10.1016/S0140-6736(15)60647-X
[Indexed for MEDLINE]
Free PMC Article

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