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Environ Health Prev Med. 2015 Jul;20(4):287-93. doi: 10.1007/s12199-015-0463-5. Epub 2015 May 5.

Effects of extremely low-frequency electromagnetic fields (ELF-EMF) exposure on B6C3F1 mice.

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  • 1Department of Physiopathology and Gastrointestinal Surgery, Guilin Medical University, Guilin, 541004, Guangxi, China.

Abstract

OBJECTIVE:

Long-term exposure study was conducted to investigate the effects of extremely low-frequency electromagnetic field on the tumor promotion process and fertility.

METHODS:

Ten pregnant C57BL/6NCrj mice were exposed to 50 Hz field 500 mG for 1 week (12 h per day), and 24 male and 42 female B6C3F1mice born from them were further exposed up to 15.5 months. As a control group, 10 pregnant mice were bred without exposure, and 30 produced male and 32 female mice were observed without exposure for the same period.

RESULTS:

Mean body weights of exposed groups of male and female mice were decreased significantly than those of the control groups. In exposed mice, there was no increased incidence of liver and lung tumor. In female mice, the incidence of chronic myeloid leukemia [3/42 (7%)] in the exposed group was significantly greater than in the control group. The size of seminiferous tubules in the EMF exposed groups were significantly less than the control group.

CONCLUSIONS:

These data support the hypothesis that long-term exposure of 50 Hz magnetic fields is a significant risk factor for neoplastic development and fertility in mice.

PMID:
25939981
PMCID:
PMC4491062
DOI:
10.1007/s12199-015-0463-5
[PubMed - indexed for MEDLINE]
Free PMC Article
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