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Bull Soc Pathol Exot. 2015 Mar;108(2):120-3. doi: 10.1007/s13149-015-0420-y. Epub 2015 Feb 27.

[Effect of a large scale community-based distribution of artemether-lumefantrine on its therapeutic efficacy among children living in a rural area of Burkina Faso].

[Article in French]

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Groupe de recherche action en santé (GRAS), 06 BP 10248, Ouagadougou 06, Burkina Faso,


This study aimed to assess the effect of an integrated community case management of malaria and pneumonia programme (iCCMmp) on the efficacy of artemether-lumefantrine (AL). Thus, we carried out two open label and unique centre clinical trials, before and after the iCCMmp, on the therapeutic efficacy of AL. A total of 210 children aged 6-59 months, were included in the study, 105 before and 105 after the iCCMmp. The adequate clinical and parasitological response was 90.5% and 86.7% respectively before and after the iCCMmp (p value = 0.516). Our findings reported no effect of iCCMmp on the therapeutic efficacy of the AL.

[Indexed for MEDLINE]

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