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Bull Soc Pathol Exot. 2015 Mar;108(2):120-3. doi: 10.1007/s13149-015-0420-y. Epub 2015 Feb 27.

[Effect of a large scale community-based distribution of artemether-lumefantrine on its therapeutic efficacy among children living in a rural area of Burkina Faso].

[Article in French]

Author information

1
Groupe de recherche action en santé (GRAS), 06 BP 10248, Ouagadougou 06, Burkina Faso, gras@fasonet.bf.

Abstract

This study aimed to assess the effect of an integrated community case management of malaria and pneumonia programme (iCCMmp) on the efficacy of artemether-lumefantrine (AL). Thus, we carried out two open label and unique centre clinical trials, before and after the iCCMmp, on the therapeutic efficacy of AL. A total of 210 children aged 6-59 months, were included in the study, 105 before and 105 after the iCCMmp. The adequate clinical and parasitological response was 90.5% and 86.7% respectively before and after the iCCMmp (p value = 0.516). Our findings reported no effect of iCCMmp on the therapeutic efficacy of the AL.

PMID:
25925810
DOI:
10.1007/s13149-015-0420-y
[Indexed for MEDLINE]

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