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Acta Cytol. 2015;59(2):207-12. doi: 10.1159/000381055. Epub 2015 Apr 23.

Evaluation of a New Automated Processing System (TACAS™ Pro) for Liquid-Based Procedures.

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Department of Cancer Detection for Females, Kanagawa Health Service Association, Yokohama, Japan.



To evaluate a fully automated processing system (TACAS™ Pro) for liquid-based procedures (LBPs).


Materials were 3,483 and additionally 502 specimens that were taken at Kanagawa Health Service Association. Specimens obtained with a Cervex-Brush® were first smeared to glass slides using one side of the brush and then processed to TACAS Pro.


(1) The microscopy watching time per normal case was 3.65 ± 0.85 min in the conventional procedure, whereas in the LBP it was 1.95 ± 0.60 min, and the latter reduced workload to 53%. (2) The handling time of TACAS Pro per day was 2 h and 25.8 min. The workload at a laboratory offset it and revealed the work saving to be 63.8%. (3) Unsatisfactory rates were 0% in the conventional procedure, whereas in the LBP it was 1.88% at first. The latter rate decreased to 0.5% after system improvement. (4) Specimens which may disturb microscopy analysis were found in 1.06%, including 3 cases of possible carry-over of cells to the following slides. An additional study with the revised system confirmed no carry-over. (5) Incidences of abnormal cytology were consistent between the two methods.


The revised automated processing system TACAS Pro is a feasible and useful LBP and reduces the workload of cytology laboratories.

[Indexed for MEDLINE]

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