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Med Hypotheses. 2015 Aug;85(2):237-8. doi: 10.1016/j.mehy.2015.04.014. Epub 2015 Apr 20.

Eumelanin-driven production of molecular hydrogen: A novel element of skin defense?

Author information

1
University of Novi Sad, Lovcenska 16, 21000 Novi Sad, Serbia. Electronic address: sergej.ostojic@chess.edu.rs.

Abstract

Molecular hydrogen (H2, dihydrogen) has been recognized as a unique cell protectant. Dihydrogen protects tissues against oxidative injuries by selectively reducing reactive oxygen species (ROS). It seems that melanin, natural pigment of skin and hair, might produce endogenous hydrogen. The protective role of skin melanin (eumelanin) could be due to its capacity for molecular hydrogen production. An effective pooling of dihydrogen by eumelanin should be considered as a novel element of skin defense system against oxidative stress-related disorders.

PMID:
25920542
DOI:
10.1016/j.mehy.2015.04.014
[Indexed for MEDLINE]

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