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Clin Case Rep. 2015 Apr;3(4):217-26. doi: 10.1002/ccr3.201. Epub 2015 Feb 2.

Polyclonal hyperviscosity syndrome in IgG4-related disease and associated conditions.

Author information

1
Department of Medicine, University of British Columbia Vancouver, British Columbia, Canada.
2
Department of Pathology and Laboratory Medicine, University of British Columbia Vancouver, British Columbia, Canada.
3
Department of Dermatology, University of Tokyo Tokyo, Japan.

Abstract

Polyclonal hyperviscosity syndrome (HVS) is rare and has been reported in various disorders of immune dysregulation and lymphoid hyperplasia. IgG4-Related Disease (IgG4-RD) is an emerging disorder often associated with exuberant hypergammaglobulinemia, and this review of seven cases establishes IgG4-RD as an important cause of polyclonal HVS.

KEYWORDS:

Hyperviscosity syndrome; IgG4 related disease; polyclonal hyperviscosity

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