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Subst Abus. 2016;37(1):255-69. doi: 10.1080/08897077.2015.1023484. Epub 2015 Apr 20.

Cannabis withdrawal and sleep: A systematic review of human studies.

Author information

1
a National Cannabis Prevention and Information Centre , UNSW Medicine , Randwick , New South Wales , Australia.

Abstract

BACKGROUND:

Sleep problems during withdrawal from cannabis use are a common experience. The details regarding how abstinence from cannabis impacts sleep are not well described. This article reviews the literature including a measure of cannabis withdrawal and sleep in humans.

METHODS:

A literature search using a set of cannabinoid and sleep-related terms was conducted across 8 electronic databases. Human studies that involved the administration of cannabinoids and at least 1 quantitative sleep-related measure were included. Review articles, opinion pieces, letters or editorials, case studies (final N < 8), published abstracts, posters, and non-English articles were excluded. Thirty-six publications were included in the review.

RESULTS:

Sleep was frequently interrupted during cannabis withdrawal, although the specific mechanisms of disruption remain unclear.

CONCLUSIONS:

Methodological issues in the majority of studies to date preclude any definitive conclusion on the specific aspects of sleep that are affected.

KEYWORDS:

Cannabis; insomnia; marijuana; sleep; withdrawal

PMID:
25893849
DOI:
10.1080/08897077.2015.1023484
[Indexed for MEDLINE]

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