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Drug Alcohol Depend. 2015 Jul 1;152:194-200. doi: 10.1016/j.drugalcdep.2015.03.039. Epub 2015 Apr 13.

Incidence and prevalence of hepatitis c virus infection among persons who inject drugs in New York City: 2006-2013.

Author information

1
The Graduate Center at the City University of New York, 365 Fifth Avenue, New York, NY 10016, USA; Center for Drug Use and HIV Research, New York, NY, USA. Electronic address: ae.jordan@nyu.edu.
2
Center for Drug Use and HIV Research, New York, NY, USA; Mount Sinai Beth Israel, Baron Edmond de Rothschild Chemical Dependency Institute, 120 Water St, Floor 24, New York, NY 10038, USA.
3
City University of New York, Hunter College, 2180 Third Avenue, New York, NY 10035, USA.
4
Center for Drug Use and HIV Research, New York, NY, USA; Mount Sinai Beth Israel, 120 East 16th Street, New York, NY 10003, USA.

Abstract

BACKGROUND:

Hepatitis C virus infection is a source of significant preventable morbidity and mortality among persons who inject drugs (PWID). We sought to assess trends in hepatitis C virus (HCV) infection among PWID from 2006 to 2013 in New York City (NYC).

METHODS:

Annual cross-sectional surveys of PWID entering a large drug abuse treatment program were performed. Risk behavior questionnaires were administered, and HIV and HCV testing were conducted. Comparisons were made with prior prevalence and incidence estimates in 1990-1991 and 2000-2001 reflecting different periods of combined prevention and treatment efforts.

RESULTS:

HCV prevalence among PWID (N: 1535) was 67% (95% CI: 66-70%) during the study period, and was not significantly different from that observed in 2000-2001. The estimated HCV incidence among new injectors (persons injecting for ≤6 years) during 2006-2013 was 19.5/100 PYO (95% CI: 17-23) and did not differ from that observed in 2000-2001 (18/100 PYO, 95% CI: 14-23/100).

CONCLUSIONS:

Despite the expansion of combined prevention programming between 2000-2001 and 2006-2013, HCV prevalence remained high. Estimated HCV incidence among new injectors also remained high, and not significantly lower than in 2000-2001, indicating that expanded combined prevention efforts are needed to control the HCV epidemic among PWID in NYC.

KEYWORDS:

Hepatitis C virus infection; Medication assisted treatment; Methadone maintenance treatment; Needle/syringe exchange program; People who inject drugs

PMID:
25891230
PMCID:
PMC4458155
DOI:
10.1016/j.drugalcdep.2015.03.039
[Indexed for MEDLINE]
Free PMC Article

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