Send to

Choose Destination
Rev Esp Cardiol (Engl Ed). 2015 Nov;68(11):968-75. doi: 10.1016/j.rec.2014.11.024. Epub 2015 Apr 15.

Disability-adjusted Life Years Lost to Ischemic Heart Disease in Spain.

Author information

Centro Nacional de Epidemiología, Instituto de Salud Carlos III, Red de Investigación en Servicios de Salud en Enfermedades Crónicas (REDISSEC), Madrid, Spain. Electronic address:
Unidad Docente de Medicina Familiar y Comunitaria Este, Hospital Ramón y Cajal, Madrid, Spain.
Fundación Instituto de Investigación en Servicios de Salud, Valencia, Spain.
Servicio de Informes de Salud y Estudios, Subdirección de Promoción de la Salud y Prevención, Consejería de Sanidad, Madrid, Spain.
Departamento de Medicina Preventiva y Salud Pública, Universidad Rey Juan Carlos, Madrid, Spain.



The health indicator disability-adjusted life years combines the fatal and nonfatal consequences of a disease in a single measure. The aim of this study was to evaluate the burden of ischemic heart disease in 2008 in Spain by calculating disability-adjusted life years.


The years of life lost due to premature death were calculated using the ischemic heart disease deaths by age and sex recorded in the Spanish National Institute of Statistics and the life-table in the 2010 Global Burden of Disease study. The years lived with disability, calculated for acute coronary syndrome, stable angina, and ischemic heart failure, used hospital discharge data and information from population studies. Disability weights were taken from the 2010 Global Burden of Disease study. We calculated crude and age standardized rates (European Standard Population). Univariate sensitivity analyses were performed.


In 2008, 539 570 disability-adjusted life years were lost due to ischemic heart disease in Spain (crude rate, 11.8/1000 population; standardized, 8.6/1000). Of the total years lost, 96% were due to premature death and 4% due to disability. Among the years lost due to disability, heart failure accounted for 83%, stable angina 15%, and acute coronary syndrome 2%. In the sensitivity analysis, weighting by age was the factor that changed the results to the greatest degree.


Ischemic heart disease continues to have a huge impact on the health of our population, mainly because of premature death. The results of this study provide an overall vision of the epidemiologic situation in Spain and could serve as the basis for evaluating interventions targeting the acute and chronic manifestations of cardiac ischemia.


Años de vida ajustados por discapacidad; Burden of disease; Carga de enfermedad; Disability-adjusted life years; Isquemia miocárdica; Myocardial ischemia

[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Ediciones Doyma, S.L.
Loading ...
Support Center