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Genome Announc. 2015 Apr 16;3(2). pii: e00209-15. doi: 10.1128/genomeA.00209-15.

Complete Genome Sequences of Two Helicobacter pylori Strains from a Canadian Arctic Aboriginal Community.

Author information

1
Department of Molecular Microbiology, Washington University Medical School, St. Louis, Missouri, USA.
2
Department of Laboratory Medicine and Pathology, University of Alberta, Edmonton, Alberta, Canada.
3
Susie Husky Health Centre, Aklavik, Northwest Territories, Canada.
4
Department of Medicine, Division of Gastroenterology, University of Alberta, Edmonton, Alberta, Canada.
5
douglaseberg@gmail.com mkeelan@ualberta.ca.

Abstract

We report here the complete genome sequences of two Amerind Helicobacter pylori strains from Aklavik, Northwest Territories, Canada. One strain contains extra iron-cofactored urease genes and ~140 rearrangements in its chromosome relative to other described strains (typically differing from one another by <10 rearrangements), suggesting that it represents a novel lineage of H. pylori.

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