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J Clin Diagn Res. 2015 Feb;9(2):ZC50-3. doi: 10.7860/JCDR/2015/11526.5599. Epub 2015 Feb 1.

Comparative Evaluation of Antibacterial Efficacy of Six Indian Plant Extracts against Streptococcus Mutans.

Author information

1
Sr. Lecturer, Department of Pedodontics and Preventive Dentistry, ITS Dental College , Ghaziabad, India .
2
Reader, Department of Oral Pathology, ITS Dental College , Ghaziabad, India .
3
Professor and Head, Department of Microbiology, Santosh Medical College , Ghaziabad, India .
4
Post Graduate Student, Department of Microbiology, Santosh Medical College , Ghaziabad, India .
5
Professor and Head, Department of Pedodontics and Preventive Dentistry, Santosh Dental College , Ghaziabad, India .
6
Reader, Department of Pedodontics and Preventive Dentistry, Santosh Dental College , Ghaziabad, India .

Abstract

INTRODUCTION:

To assess the antimicrobial efficacy of six plant extracts of Indian origin often used as traditional medicine against standard strains of Streptococcus mutans.

MATERIALS AND METHODS:

The antimicrobial activity of six plant extracts was determined by the agar well diffusion method. The minimum inhibitory concentration (MIC) for the crude (raw), Organic solvent based, aqueous extracts was determined by the agar well diffusion method.

RESULTS:

Out of all the six extracts evaluated, organic solvent based and aqueous extracts of all the extracts were found to have variable antimicrobial activities against the oral pathogen. The crude extract of Garlic was the most effective against Streptococcus mutans with the highest zone of inhibition (24.62 mm) followed by the aqueous extract of Amla (19.47mm) and organic solvent based extract of Ginger (18.76 mm).

CONCLUSION:

Despite of the fact that the extracts were not pure compounds and antimicrobial results were obtained. This recommends the potency of these extracts. The figment of the derivation of antimicrobial compounds from plants seems lucrative as it will lead to the development of a phytomedicine to act against microbes.

KEYWORDS:

Antibacterial activity; Minimum inhibitory concentration; Plant extracts; Streptococcus mutans

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