Combination-therapy with concurrent deferoxamine and deferiprone is effective in treating resistant cardiac iron-loading in aceruloplasminaemia

Br J Haematol. 2015 Nov;171(3):430-2. doi: 10.1111/bjh.13401. Epub 2015 Apr 8.

Authors

Mohsin Badat¹, Banu Kaya², Paul Telfer²

Affiliations

¹ Department of Paediatric Haematology and Oncology, Barts Health NHS Trust, Royal London Hospital, London, UK. mohsin.badat@nhs.net.
² Department of Paediatric Haematology and Oncology, Barts Health NHS Trust, Royal London Hospital, London, UK.

PMID: 25855051
DOI: 10.1111/bjh.13401

No abstract available

Keywords: anaemia; chelation; iron biochemistry; iron metabolism; iron overload.

Publication types

Case Reports
Letter

MeSH terms

Adult
Ceruloplasmin / deficiency*
Deferiprone
Deferoxamine / administration & dosage*
Drug Therapy, Combination
Heart Diseases / blood
Heart Diseases / complications
Heart Diseases / drug therapy*
Humans
Iron Metabolism Disorders / blood
Iron Metabolism Disorders / complications
Iron Metabolism Disorders / drug therapy*
Iron Overload / blood
Iron Overload / complications
Iron Overload / drug therapy*
Male
Neurodegenerative Diseases / blood
Neurodegenerative Diseases / complications
Neurodegenerative Diseases / drug therapy*
Pyridones / administration & dosage*
Siderophores / administration & dosage*

Substances

Pyridones
Siderophores
Deferiprone
Ceruloplasmin
Deferoxamine

Supplementary concepts

Familial apoceruloplasmin deficiency