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Pediatr Pulmonol. 2015 Dec;50(12):1262-9. doi: 10.1002/ppul.23196. Epub 2015 Apr 2.

Caesarean Section has no impact on lung function at the age of 15 years.

Author information

1
Institute of Epidemiology I, Helmholtz Zentrum München-German Research Center for Environment Health, Neuherberg, Germany.
2
Faculty of Medicine, Ludwig-Maximilians-University of Munich, Munich, Germany.
3
Division of Metabolic and Nutritional Medicine, Dr. von Hauner Children's Hospital, University of Munich Medical Center, Munich, Germany.
4
Department of Pediatrics, Marienhospital, Wesel, Germany.
5
Dr. von Hauner Children's Hospital, Ludwig-Maximilians University of Munich, Munich, Germany.
6
Department of Pediatrics, Technical University of Munich, Munich, Germany.
7
IUF-Leibniz Research Institute for Environmental Medicine, Germany and Medical Faculty, University of Düsseldorf, Düsseldorf, Germany.

Abstract

BACKGROUND:

Epidemiological studies and meta-analyses have shown an increased risk of childhood asthma for children born by Caesarean Section (C-Section).

OBJECTIVE:

To investigate the effect of delivery by C-Section on lung function and asthma in adolescence in a population-based prospective birth cohort of healthy full term newborns.

METHODS:

Questionnaire data on mode of delivery and asthma as well as spirometric measurements were available for 1850 adolescents at the age of 15 years, who participated in a follow-up examination of the GINIplus study. Linear regression models were used to examine associations between mode of delivery and lung function parameters. Two reference populations (Lunokid and GLI) were used to calculate the standardized z-scores of lung function parameters.

RESULTS:

The mean difference in lung function parameters for adolescents born by C-Section, compared to vaginal delivery was not statistically significant. The risk for developing asthma by the age of 15 years was not higher in children born by C-Section-OR: 0.87 (95% CI: 0.57, 1.33) adjusted for sex, age, study center, and parental education level.

CONCLUSION:

C-Section was not associated with impaired lung function or an increased risk of asthma at the age of 15 years in our birth cohort of healthy full term neonates.

KEYWORDS:

C-Section; asthma; lung function

PMID:
25847609
DOI:
10.1002/ppul.23196
[Indexed for MEDLINE]

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