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J Community Hosp Intern Med Perspect. 2015 Apr 1;5(2):26645. doi: 10.3402/jchimp.v5.26645. eCollection 2015.

A case of acute generalized exanthematous pustulosis associated with polyarteritis nodosa, responding to systemic steroids.

Author information

1
Department of Medicine, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, OH, USA.
2
Department of Medicine, Louis Stokes Cleveland VA Medical Center, Cleveland, OH, USA.
3
Department of Neurology, University Hospitals Case Medical Center, Case Western Reserve University, Cleveland, OH, USA; Ayham.malkhachroum@uhhospitals.org.

Abstract

A patient with a known biopsy of polyarteritis nodosa diagnosis presented with cyclic fevers, acute kidney injury, and progression of rash from macular to pustular, worsening despite being on antibiotics, without evidence of infection on multiple cultures. The patient had a pathological diagnosis from a skin biopsy of acute generalized exanthematous pustulosis syndrome, with a total resolution of rash, fevers, and acute kidney injury on treatment with pulse steroids.

KEYWORDS:

AGEP; PAN; Pustules; Skin Lesions; Systemic Steroids

PMID:
25846351
PMCID:
PMC4387336

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