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J Am Chem Soc. 2015 Apr 22;137(15):4976-9. doi: 10.1021/jacs.5b02700. Epub 2015 Apr 10.

Catalytic mesoporous Janus nanomotors for active cargo delivery.

Author information

1
†Max Planck Institute for Intelligent Systems Institution, Heisenbergstraße 3, 70569 Stuttgart, Germany.
2
‡Institució Catalana de Recerca i EstudisAvancats (ICREA), Pg. Lluís Companys 23, 08010, Barcelona, Spain.
3
§Institut de Bioenginyeria de Catalunya (IBEC), Baldiri i Reixac 10-12, 08028 Barcelona, Spain.

Abstract

We report on the synergy between catalytic propulsion and mesoporous silica nanoparticles (MSNPs) for the design of Janus nanomotors as active cargo delivery systems with sizes <100 nm (40, 65, and 90 nm). The Janus asymmetry of the nanomotors is given by electron beam (e-beam) deposition of a very thin platinum (2 nm) layer on MSNPs. The chemically powered Janus nanomotors present active diffusion at low H2O2 fuel concentration (i.e., <3 wt %). Their apparent diffusion coefficient is enhanced up to 100% compared to their Brownian motion. Due to their mesoporous architecture and small dimensions, they can load cargo molecules in large quantity and serve as active nanocarriers for directed cargo delivery on a chip.

PMID:
25844893
PMCID:
PMC4440854
DOI:
10.1021/jacs.5b02700
[Indexed for MEDLINE]
Free PMC Article
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