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Int J Cardiol. 2015;187:273-80. doi: 10.1016/j.ijcard.2015.03.359. Epub 2015 Mar 26.

Novel insights into an "old" phenomenon: the no reflow.

Author information

  • 1Ospedale Valduce, Como, Italy. Electronic address: durante.alessandro@gmail.com.
  • 2Universit√† Vita-Salute San Raffaele, Milan, Italy.

Abstract

Coronary artery diseases and particularly acute myocardial infarction are the leading causes of mortality and morbidity in western countries. Despite the achievements of the last decades with the advent of double antiplatelet therapy, new antithrombotics and reperfusion strategies (either pharmacological or mechanical), many patients still have adverse cardiovascular events after ST-segment elevation acute myocardial infarction; at least some of these adverse events are related to the no reflow phenomenon that occurs after primary percutaneous coronary intervention. In our review we will discuss the various aspects of this phenomenon.

KEYWORDS:

Cardiac magnetic resonance; Microvascular obstruction; Myocardial infarction; No reflow; Percutaneous coronary intervention; STEMI

PMID:
25838230
DOI:
10.1016/j.ijcard.2015.03.359
[PubMed - indexed for MEDLINE]
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