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Aust N Z J Public Health. 2015 Apr;39(2):162-7. doi: 10.1111/1753-6405.12352.

Sociodemographic differences in the incidence of oropharyngeal and oral cavity squamous cell cancers in New Zealand.

Author information

1
Section of Epidemiology and Biostatistics, School of Population Health, Faculty of Medical and Health Sciences, University of Auckland, New Zealand; Department of Obstetrics and Gynaecology, School of Medicine, University of Auckland, New Zealand.

Abstract

OBJECTIVE:

To determine whether the incidence of oropharyngeal and oral cavity squamous cell cancers differs by subsite, age, gender, ethnicity and social deprivation.

METHODS:

Using data from the New Zealand cancer registry, a retrospective review was undertaken of incident cases with a histological diagnosis of invasive squamous cell carcinoma (SCC) in the oral cavity or oropharynx.

RESULTS:

During the period 1981-2010, rates of oropharyngeal cancers (OPC) and oral cavity cancers (OCC) were higher among males and increased with age. The rapid rise in male OPCs was observed in those aged 40-49, 50-59, 60-69 and ≥70 years old. Overall and by gender, Māori had higher OPC rates but lower OCC rates than European/other ethnicities, whereas the inverse was apparent among Pacific Peoples. An upward trend in OPC and OCC rates with increasing deprivation was observed both overall and by gender.

CONCLUSIONS:

The recent rapid rise in male oropharyngeal SCCs occurred primarily among those aged ≥40 years old.

IMPLICATIONS:

Given oropharyngeal SCCs are more strongly associated with human papillomaviruses (HPV) than OCCs, OPC prevention may be enhanced through HPV vaccination and public health awareness. Clinically, as HPV-related OPCs have a better prognosis and response to radiotherapy, an improvement in survival rates can be predicted.

KEYWORDS:

demographic factors; incidence; oral cavity cancer; oropharyngeal cancer

PMID:
25827186
DOI:
10.1111/1753-6405.12352
[Indexed for MEDLINE]

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