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Cell. 2015 Mar 26;161(1):12-17. doi: 10.1016/j.cell.2015.02.039.

Modeling human nutrition using human embryonic stem cells.

Author information

1
Department of Stem Cell and Regenerative Biology, Harvard Stem Cell Institute, Harvard University, 7 Divinity Avenue, Cambridge MA, USA. Electronic address: benzvi@fas.harvard.edu.
2
Department of Stem Cell and Regenerative Biology, Harvard Stem Cell Institute, Harvard University, 7 Divinity Avenue, Cambridge MA, USA.

Abstract

Nutrition presents unanswered scientific questions of high public health importance. We envision model systems composed of interacting gastrointestinal and metabolic tissues derived from human embryonic stem cells, populated by gut microbiota. The culture will be embedded in 3D scaffolds, creating a controlled experimental system that enables tissue sampling and imaging.

PMID:
25815980
DOI:
10.1016/j.cell.2015.02.039
[Indexed for MEDLINE]
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