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Clin Exp Hypertens. 2015;37(6):468-72. doi: 10.3109/10641963.2015.1013117. Epub 2015 Mar 27.

Coexistence of PM2.5 and low temperature is associated with morning hypertension in hypertensives.

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a Division of Cardiovascular Medicine, Department of Medicine , Jichi Medical University , Tochigi , Japan.


We tested the hypothesis that concentration of PM2.5 is associated with home BP level. We analyzed home BP data for 91 consecutive days in 40 hypertensives. PM2.5 solely was not correlated with home BP levels, but low temperature was associated with a 1.6-fold increased likelihood of morning hypertension (p < 0.001) under the condition of high PM2.5 concentration. In addition, coexistence of low temperature and high PM2.5 was associated with a 2.3-fold increased likelihood of morning hypertension (p < 0.001) compared with high temperature and low PM2.5 condition. Environmental and meteorological factors could be important causes of enhanced home BP elevation.


Air pollution; fine particulate matter with a diameter <2.5 µm; home BP; morning hypertension; temperature

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