Sodium phenylbutyrate coated granules (Pheburane). Defective urea synthesis: a welcome formulation

Prescrire Int. 2015 Feb;24(157):35-6.

Abstract

Compared with Ammonaps granules, Pheburane coated granules mask the unpleasant taste of sodium phenylbutyrate. A more precise dosing device is provided with the coated granules than with the uncoated granules (Ammonaps).

MeSH terms

  • Administration, Oral
  • Chemistry, Pharmaceutical
  • Drug Dosage Calculations
  • Humans
  • Phenylbutyrates / administration & dosage*
  • Phenylbutyrates / adverse effects
  • Phenylbutyrates / chemistry
  • Phenylbutyrates / pharmacokinetics
  • Powders
  • Taste / drug effects
  • Therapeutic Equivalency
  • Urea Cycle Disorders, Inborn / drug therapy*
  • Urea Cycle Disorders, Inborn / enzymology

Substances

  • Phenylbutyrates
  • Powders
  • 4-phenylbutyric acid