Format

Send to

Choose Destination
Lupus. 2015 Apr;24(4-5):392-9. doi: 10.1177/0961203314560205.

Environmental estrogen bisphenol A and autoimmunity.

Author information

1
1st Department of Internal Medicine, Faculty of Medicine, P. J. Šafárik University, Košice, Slovakia.
2
Department of Medical Physiology, Faculty of Medicine, P. J. Šafárik University, Košice, Slovakia.
3
Department of Medical and Clinical Biochemistry and LABMED, Faculty of Medicine, P. J. Šafárik University, Košice, Slovakia.
4
1st Department of Internal Medicine, Faculty of Medicine, P. J. Šafárik University, Košice, Slovakia ivica.lazurova@upjs.sk.

Abstract

Over the past few years, there has been evidence of the increasing prevalence of autoimmune diseases. Autoimmune diseases consist of many complex disorders of unknown etiology resulting in immune responses to self-antigens. The immune system, and its function, is under complex and integrated control and its disruption can be triggered by multiple factors. Autoimmunity development is influenced by multiple factors and is thought to be a result of interactions between genetic and environmental factors. Here, we review the role of a specific environmental factor, bisphenol A (BPA), in the pathogenesis of autoimmune diseases. BPA belongs to the group of environmental estrogens that have been identified as risk factors involved in the development of autoimmune diseases.

KEYWORDS:

Autoimmunity; bisphenol A; environmental estrogens

PMID:
25801882
DOI:
10.1177/0961203314560205
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Atypon
Loading ...
Support Center