Format

Send to

Choose Destination
Eur J Obstet Gynecol Reprod Biol. 2015 May;188:70-3. doi: 10.1016/j.ejogrb.2015.03.001. Epub 2015 Mar 9.

Impact of osteopathic manipulative therapy on quality of life of patients with deep infiltrating endometriosis with colorectal involvement: results of a pilot study.

Author information

1
Service de Gynécologie-Obstétrique et Reproduction Humaine, Hôpital Tenon, Assistance Publique des Hôpitaux de Paris, Université Pierre et Marie Curie Paris 6, GRC-6 UPMC, Centre Expert En Endométriose (C3E), Paris, France; Institut Privé d'Enseignement Ostéopathique (IPEO), 5/13 rue Auger, Pantin, France.
2
Institut Privé d'Enseignement Ostéopathique (IPEO), 5/13 rue Auger, Pantin, France.
3
Service de Gynécologie-Obstétrique et Reproduction Humaine, Hôpital Tenon, Assistance Publique des Hôpitaux de Paris, Université Pierre et Marie Curie Paris 6, GRC-6 UPMC, Centre Expert En Endométriose (C3E), Paris, France.
4
Service de Gynécologie-Obstétrique et Reproduction Humaine, Hôpital Tenon, Assistance Publique des Hôpitaux de Paris, Université Pierre et Marie Curie Paris 6, GRC-6 UPMC, Centre Expert En Endométriose (C3E), Paris, France; UMRS938, Université Pierre et Marie Curie, Paris 6, France.
5
Service de Gynécologie-Obstétrique et Reproduction Humaine, Hôpital Tenon, Assistance Publique des Hôpitaux de Paris, Université Pierre et Marie Curie Paris 6, GRC-6 UPMC, Centre Expert En Endométriose (C3E), Paris, France; UMRS938, Université Pierre et Marie Curie, Paris 6, France. Electronic address: emile.darai@tnn.aphp.fr.

Abstract

OBJECTIVE:

A prospective pilot study to evaluate the potential role of osteopathic manipulative therapy (OMT) on quality of life (QOL) of patients with Deep Infiltrating Endometriosis (DIE) and colorectal involvement.

STUDY DESIGN:

Twenty patients with DIE and colorectal infiltration completed the SF-36 QOL questionnaire before and after undergoing OMT.

RESULTS:

The median age (range) of the patients was 30.4 years (22-39). Thirty-five percent of the patients had undergone previous surgery for endometriosis and 70% were on medical treatment. Fifteen of the 20 patients (75%) completed the protocol. There was no difference in the epidemiological characteristics or in the pre-OMT Physical Component Summary (PCS) and Mental Component Summary (MCS) of the SF-36 questionnaire between patients who completed the protocol or not. After a mean period of 24 days (15-53), a significant improvement in PCS (p=0.03) and MCS (p=0.0009) compared to pre-OMT values was observed giving a success rate of 80% and 60% in intention-to-treat, respectively.

CONCLUSION:

Our results support that OMT can improve QOL of patients with DIE and colorectal involvement. Moreover, this pilot study can serve to determine power calculations for future randomized trials.

KEYWORDS:

Colorectal endometriosis; Deep infiltrating endometriosis; Endometriosis; Osteopathic manipulative therapy; Quality of life; SF-36

PMID:
25796057
DOI:
10.1016/j.ejogrb.2015.03.001
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center