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Cancer Res. 2015 Apr 1;75(7):1177-80. doi: 10.1158/0008-5472.CAN-14-2902. Epub 2015 Mar 18.

26th Pezcoller symposium: cancers driven by hormones.

Author information

1
Medical Oncology, Dana Farber Cancer Institute, Boston, Massachusetts.
2
Howard Hughes Medical Institute, University of Michigan, Ann Arbor, Michigan.
3
Institute of Cell Biology and Neurobiology, National Research Council, Rome, Italy.
4
Cancer Biology, Dana Farber Cancer Institute, Boston, Massachusetts.
5
Center for Molecular Oncologic Pathology, Dana Farber Cancer Institute, Boston, Massachusetts.
6
Central Clinical Research, Freiburg University Medical Center, Freiburg, Germany.
7
Medical Oncology, Dana Farber Cancer Institute, Boston, Massachusetts. enrico_mihich@dfci.harvard.edu.

Abstract

This symposium was held in Trento, Italy, on June 19-21, 2014, and was focused on advances in biology, physiology, and pathology of neoplasms affected by hormones, especially breast and prostate cancers. The stem cell function, the genetic and epigenetic interactions with hormones, the mechanisms of estrogen receptor transcription, biochemical markers and therapeutic targets in breast cancer, promotion of breast cancer carcinogenesis by progesterone, the basis for prostate cancer progression and the relevance of DNA repair processes, androgen receptor programming during prostate carcinogenesis, the metabolic stress role in tumor survival, and the diagnostic use of imaging in prostate cancer were discussed.

PMID:
25788695
DOI:
10.1158/0008-5472.CAN-14-2902
[Indexed for MEDLINE]
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