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J Clin Microbiol. 2015 Jun;53(6):1938-41. doi: 10.1128/JCM.00261-15. Epub 2015 Mar 18.

Comparison of the AmpliVue, BD Max System, and illumigene Molecular Assays for Detection of Group B Streptococcus in Antenatal Screening Specimens.

Author information

1
Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.
2
Department of Pathology and Laboratory Medicine, Santa Clara Valley Medical Center, San Jose, California, USA.
3
Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at UCLA, Los Angeles, California, USA rhumphries@mednet.ucla.edu.

Abstract

The performances of the AmpliVue, BD Max, and illumigene group B Streptococcus (GBS) nucleic acid amplification tests (NAATs) were compared to that of enriched culture for detection of GBS in antenatal screening specimens. Two hundred specimens were tested simultaneously with the NAATs, following 18 to 24 h of Lim broth enrichment; 15% of specimens were culture positive for GBS, whereas 31.5% were positive by at least one NAAT. All three NAATs were more sensitive (sensitivity, 90.9 to 100%) than culture (sensitivity, 53.6%).

PMID:
25788551
PMCID:
PMC4432075
DOI:
10.1128/JCM.00261-15
[Indexed for MEDLINE]
Free PMC Article

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