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Eur J Neurol. 2015 Jun;22(6):967-72. doi: 10.1111/ene.12693. Epub 2015 Mar 19.

Susceptibility vessel sign on T2* magnetic resonance imaging and recanalization results of mechanical thrombectomy with stent retrievers: a multicentre cohort study.

Author information

1
Department of Neuroradiology, INSERM UMR S894, Université Paris Descartes, Sorbonne Paris Cité, Hôpital Sainte-Anne, Paris, France; Department of Neuroradiology, CHU Reims, Hôpital Maison Blanche, Université de Champagne-Ardenne, Reims, France.

Abstract

BACKGROUND AND PURPOSE:

The susceptibility vessel sign (SVS) on T2*-weighted magnetic resonance imaging has been reported in several studies as a negative predictor of early recanalization after intravenous thrombolysis. The meaning of SVS regarding the results of mechanical thrombectomy with stent retrievers was investigated.

METHODS:

Susceptibility vessel sign presence and length were studied in 153 acute ischaemic stroke patients (82 men; mean ± SD age 59 ± 17 years, baseline National Institutes of Health Stroke Scale score 17.2 ± 6.5) from three stroke centres, treated with either mechanical thrombectomy alone (n = 84) or bridging therapy (n = 69). Variables were compared between recanalizers, defined as thrombolysis in cerebral infarction (TICI) scores ≥2b, and non-recanalizers (TICI<2b).

RESULTS:

The SVS was present in 113 (73.8%) patients. There was no association between the presence of SVS and recanalization, obtained in 86 (56.2%) patients, in the whole population [odds ratio (OR) 1.24, 95% confidence interval (CI) 0.53-2.92, P = 0.84) and in treatment subgroups (bridging: OR = 0.91, 95% CI 0.29-2.87, P = 1.0; thrombectomy alone: OR = 1.85, 95% CI 0.48-7.16, P = 0.54). However, in SVS+ patients, recanalization decreased with SVS length (OR 0.94 for each additional mm, 95% CI 0.89-0.99; P = 0.02).

CONCLUSIONS:

The success of recanalization in acute stroke patients treated with stent retrievers was related to thrombus length but not to the presence of SVS.

KEYWORDS:

ischaemic stroke; magnetic resonance imaging; thrombectomy; thrombus

PMID:
25786977
DOI:
10.1111/ene.12693
[Indexed for MEDLINE]

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