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Curr Biol. 2015 Mar 16;25(6):R234-R236. doi: 10.1016/j.cub.2015.02.003.

Neurodegeneration: paying it off with sleep.

Author information

1
Department of Biology, University of Nevada, Reno. Reno, NV 89557, USA. Electronic address: alexckeene@gmail.com.
2
Department of Pharmacology, Biomedical Sciences Graduate Program, Neurosciences Graduate Program, and Center for Chronobiology, University of California, San Diego, La Jolla, CA 92093-0636, USA.

Abstract

A new study in fruit flies suggests modulation of neural activity links sleep and Alzheimer's disease. Both sleep loss and amyloid beta increase neural excitability, which reinforces the accumulation of amyloid beta and shortens lifespan.

PMID:
25784043
PMCID:
PMC4381801
DOI:
10.1016/j.cub.2015.02.003
[Indexed for MEDLINE]
Free PMC Article

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