Format

Send to

Choose Destination
Joint Bone Spine. 2015 Oct;82(5):362-4. doi: 10.1016/j.jbspin.2015.01.020. Epub 2015 Mar 13.

New onset of articular inflammatory manifestations in patients with hidradenitis suppurativa under treatment with infliximab.

Author information

1
Department of rheumatology, university hospital of Nice, 151, route de Saint-Antoine-de-Ginestière, 06200 Nice, France. Electronic address: acquacalda.e@chu-nice.fr.
2
Department of rheumatology, university hospital of Nice, 151, route de Saint-Antoine-de-Ginestière, 06200 Nice, France.
3
Department of dermatology, university hospital of Nice, 06200 Nice, France; Inserm, U1065, centre méditerranéen de médecine moléculaire (C3M), team 12, 06100 Nice, France.

Abstract

OBJECTIVES:

Severe hidradenitis suppurativa (HS), under infliximab, can be associated with different forms of arthritis whose mechanism is unclear. Our objective is to establish the frequency and clinical presentation of new-onset arthritis in HS under infliximab.

METHODS:

Severe HS patients under infliximab were followed up between 2007-2012. New articular inflammatory manifestations were investigated by rheumatologist.

RESULTS:

Three patients over eleven developed a polyarthritis. Mean duration of arthritis was 3 months. At treatment's stop: 2 patients improved and 1 relieved with adalimumab.

CONCLUSION:

The inflammatory rheumatism's frequency in HS under infliximab seems underestimated.

KEYWORDS:

Hidradenitis suppurativa; Infliximab; Paradoxical reaction; Spondyloarthritis

PMID:
25776450
DOI:
10.1016/j.jbspin.2015.01.020
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Elsevier Science
Loading ...
Support Center