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Prev Med. 2015 Jun;75:49-55. doi: 10.1016/j.ypmed.2015.03.009. Epub 2015 Mar 12.

Healthy excessive weight in Portuguese women 4 years after delivery of a liveborn.

Author information

1
EPIUnit - Institute of Public Health, University of Porto, Porto, Portugal. Electronic address: alhenriques@med.up.pt.
2
EPIUnit - Institute of Public Health, University of Porto, Porto, Portugal; Department of Clinical Epidemiology, Predictive Medicine and Public Health, University of Porto Medical School, Porto, Portugal.
3
EPIUnit - Institute of Public Health, University of Porto, Porto, Portugal; Department of Clinical Epidemiology, Predictive Medicine and Public Health, University of Porto Medical School, Porto, Portugal; Department of Clinical Pathology, Centro Hospitalar São João, Porto, Portugal.

Abstract

OBJECTIVE:

To quantify the prevalence of healthy excessive weight and determinants of metabolic profile, considering women's reproductive life.

METHODS:

We evaluated 1847 mothers of a birth cohort assembled after delivery and reevaluated 4years later. A healthy profile was defined as the absence of hypertension, diabetes, dyslipidemia, C-reactive protein <3mg/l and being below the second tertile of HOMA-IR. Adjusted odds ratios (OR) and confidence intervals (95% CI) were computed using multinomial logistic regression, taking women with normal BMI as the reference category of the outcome.

RESULTS:

Four years after delivery, 47% of women had normal BMI, 33% were overweight and 20% obese. In each BMI class, 61%, 33% and 12% presented a healthy metabolic profile, respectively. Family history of CVD/cardiometabolic risk factors was associated with a higher probability of obesity with a not healthy metabolic profile (OR=1.39 95% CI: 0.98-1.98). Women who breastfed the enrolled child for >26weeks and practiced physical exercise were less likely to be obese and metabolically unhealthy (OR=0.39 95% CI: 0.23-0.68; OR=0.48 95% CI: 0.33-0.70, respectively), with no effect on healthy excessive weight.

CONCLUSIONS:

These results support the existence of a healthy excessive weight phenotype in women after motherhood, influenced by anthropometrics, genetic and lifestyles characteristics.

KEYWORDS:

Excessive weight; Healthy metabolic profile; Motherhood

PMID:
25770435
DOI:
10.1016/j.ypmed.2015.03.009
[Indexed for MEDLINE]

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