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Muscles Ligaments Tendons J. 2015 Feb 5;4(4):461-6. eCollection 2014 Oct-Dec.

Platelet-rich plasma treatment improves outcomes for chronic proximal hamstring injuries in an athletic population.

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University of Colorado Hospital Department of Orthopedic Surgery, Division of Sports Medicine and Shoulder Surgery, Aurora, CO, USA.
Boulder Community Hospital, Department of Musculoskeletal Radiology, Boulder, CO, USA.



chronic proximal hamstring tendinopathies is a disabling activity related condition. Currently, there is no well-accepted or extensively documented non-operative treatment option that provides consistently successful results.


to evaluate the efficacy of ultrasound guided platelet-rich plasma injections in treating chronic proximal hamstring tendinopathies.


a total of 18 consecutive patients were retrospectively analyzed. All patients received a single injection of platelet rich plasma via ultra-sound guidance by a single radiologist. Outcome measures included a questionnaire evaluating previous treatments, visual analog scale (VAS) for pain, subjective improvement, history of injury, and return to activity.


the patient population included 12 females and 6 males. The average age at the time of the injection was 42.6 years (19-60). Provocative activities included running, biking, swimming. The average body mass index of patients was 22.9 (17.2-30.2). The average time of chronic pain prior to receiving the first injection was 32.6 months (6-120). All patients had attempted other forms of non-surgical treatment prior to entering the study. The average VAS pre-injection was 4.6 (0-8). Six months after the injection, 10/18 patients had 80% or greater improvement in their VAS. Overall, the average improvement was 63% (5-100). The only documented side effect was post-injection discomfort that resolved within seventy-two hours.


chronic hamstring tendinopathy is a debilitating condition secondary to the pain, which limits an athlete's ability to perform. For refractory cases of chronic insertional proximal hamstring injuries, platelet-rich plasma injections are safe and show benefit in the majority of patients in our study, allowing return to pre-injury activities.


Case series; Level of evidence, 4.


outcome; overuse injury; platelet rich plasma; proximal ham-string tendinopathy; proximal hamstring tendinitis


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