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Mult Scler. 2015 Aug;21(9):1184-94. doi: 10.1177/1352458515576261. Epub 2015 Mar 12.

Distress improves after mindfulness training for progressive MS: A pilot randomised trial.

Author information

1
Department of Psychology, City University, London, UK angeliki.bogosian.1@city.ac.uk.
2
Psychology Department, Institute of Psychiatry, Psychology & Neuroscience, King's College London, UK.
3
Centre for the Economics of Mental and Physical Health, Institute of Psychiatry, Psychology & Neuroscience, King's College London, UK.
4
Neurology Department, King's College Hospital, London, UK.

Abstract

BACKGROUND:

Mindfulness-based interventions have been shown to effectively reduce anxiety, depression and pain in patients with chronic physical illnesses.

OBJECTIVES:

We assessed the potential effectiveness and cost-effectiveness of a specially adapted Skype distant-delivered mindfulness intervention, designed to reduce distress for people affected by primary and secondary progressive MS.

METHODS:

Forty participants were randomly assigned to the eight-week intervention (n = 19) or a waiting-list control group (n = 21). Participants completed standardised questionnaires to measure mood, impact of MS and symptom severity, quality of life and service costs at baseline, post-intervention and three-month follow-up.

RESULTS:

Distress scores were lower in the intervention group compared with the control group at post-intervention and follow-up (p < 0.05), effect size -0.67 post-intervention and -0.97 at follow-up. Mean scores for pain, fatigue, anxiety, depression and impact of MS were reduced for the mindfulness group compared with control group at post-therapy and follow-up; effect sizes ranged from -0.27 to -0.99 post-intervention and -0.29 to -1.12 at follow-up. There were no differences in quality-adjusted life years, but an 87.4% probability that the intervention saves on service costs and improves outcome.

CONCLUSIONS:

A mindfulness intervention delivered through Skype video conferences appears accessible, feasible and potentially effective and cost-effective for people with progressive MS.

KEYWORDS:

Multiple sclerosis; anxiety; depression; distress; mindfulness; pilot randomised control trial; progressive

PMID:
25767124
DOI:
10.1177/1352458515576261
[Indexed for MEDLINE]

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