Format

Send to

Choose Destination
J Postgrad Med. 2015 Apr-Jun;61(2):110-1. doi: 10.4103/0022-3859.153105.

Iatrogenic nocturnal eneuresis – an overlooked side effect of anti histamines?

Author information

1
Allergology and Immunology Unit, University of Messina, Messina, Italy.

Abstract

Nocturnal enuresis is a common disorder in childhood, but its pathophysiological mechanisms have not been fully elucidated. Iatrogenic nocturnal enuresis has been described following treatment with several psychotropic medications. Herein, we describe a 6-year-old child who experienced nocturnal enuresis during treatment with the antihistamine cetirizine. Drug rechallenge was positive. Several neurotransmitters are implicated in the pathogenesis of nocturnal enuresis, including noradrenaline, serotonin and dopamine. Antihistamine treatment may provoke functional imbalance of these pathways resulting in incontinence.

PMID:
25766344
PMCID:
PMC4943431
DOI:
10.4103/0022-3859.153105
[Indexed for MEDLINE]
Free PMC Article

Supplemental Content

Full text links

Icon for Medknow Publications and Media Pvt Ltd Icon for PubMed Central
Loading ...
Support Center