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Cell Host Microbe. 2015 Mar 11;17(3):279-82. doi: 10.1016/j.chom.2015.02.019.

Influenza surveillance: 2014-2015 H1N1 "swine"-derived influenza viruses from India.

Author information

  • 1Department of Biological Engineering, Skolkovo-MIT Center for Biomedical Engineering, Singapore-MIT Alliance for Research and Technology, Koch Institute of Integrative Cancer Research, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, USA.
  • 2Department of Biological Engineering, Skolkovo-MIT Center for Biomedical Engineering, Singapore-MIT Alliance for Research and Technology, Koch Institute of Integrative Cancer Research, Massachusetts Institute of Technology, 77 Massachusetts Avenue, Cambridge, MA 02139, USA. Electronic address: rams@mit.edu.

Abstract

The 2014-15 H1N1 outbreak in India has reportedly led to 800 fatalities. The reported influenza hemagglutinin sequences from India indicate that these viruses contain amino acid changes linked to enhanced virulence and are potentially antigenically distinct from the current vaccine containing 2009 (Cal0709) H1N1 viral hemagglutinin.

PMID:
25766285
DOI:
10.1016/j.chom.2015.02.019
[PubMed - indexed for MEDLINE]
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